Peak problems
Nico Vonk
,
Avans+, Breda
,
The Netherlands
Level
Basic
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Troubleshooting LC, basics
How to avoid trouble
Top tips from practice
Systematic problem solving
Pressure problems
Peak problems
> No peaks
> Very small peaks.
> Back tailing peaks.
> Front tailing peaks.
> Split peaks.
> Round (double) peaks.
> Negative peaks.
> Ghost peaks.
Resolution problems
Bad column stability
Baseline problems
The pump
Injection
The column
Mobile phase
Detection
Diagnosing 'bad' chromatograms
More 'bad' LC chromatograms
How to use and regenerate columns
Bad retention time stability
LC troubleshooting advanced course
How to avoid trouble
Diagnosing 'bad' chromatograms
Before you call the service dept!
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