Abstract Injection valves are used to add sample to the high-pressure flow of an HPLC system in a quantitative and reproducible manner. A rotating stator changes the mobile phase flow path nearly instantaneously such that it passes through a pre-filled sample loop or through a sample loop bypass. Demands on the valve are stringent. Volumes must be reproducible, the valve must be durable, and must rotate quickly to minimize flow interruptions. Modern injection valves are frequently integrated with autosamplers.
KeywordsRotor, Stator, Sample loop, Partial filling, Complete filling, Load position, Inject position, Injection volume, Autosampler
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