To initiate a method
Abstract In case of non-routine problems, we need a new method.
Non-routine problems are problem that were not previously or earlier encountered in the same manner, this means that no ready-made solution is available. At that moment, a process is started, which could potentially lead to the development of a chromatographic method. However, before the actual method development can start, a number of questions need to be answered.
This initial stage of method development will be discussed using an extensive 'Checklist', attached to this chapter.
This chapter has been written by Peter Schoenmakers, Stella Brudin and Peter Pruim.
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