ST in analytical chemistry

Abstract Sample treatment (ST) is the bottleneck in most chromatographic / electrophoretic separations.
The main ST objectives discussed in this Topic are:

1. Learn technologies and techniques:
· How do they work,
· What are the applications,
· What are the advantages and limitations,
2. Possibilities to improve laboratory operations:
· Cost (labour intensive),
· Errors (accuracy, precision),
· Time,
3. Productivity issues:
· Automation,
· Parallel versus serial processing,
· On-line versus off-line,
4. Help to make the transition from SOP’s to (new) techniques a successful one:
· Criteria for choosing sample treatment techniques.

Sampling and sample preparation in analytical chemistry will be presented in a practical way to provide the analytical chemist with the necessary tools to determine low- and high-molecular-weights compounds in a variety of matrices using chromatographic / electrophoretic, spectroscopic or immunological methods.
Method development procedures will be based on the physico-chemical properties of the analyte(s) and the matrices in which these compounds are present

This chapter provides a general introduction. The upcoming chapters will provide the necessary detail.


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