Detection in ion chromatography (IC)

Abstract Ions separated by IC may lack sufficient UV absorbance so that light absorbance detectors commonly employed in HPLC cannot be used in all cases. Detection based on conductivity measurements is the preferred mode for routine work in IC, although new applications have necessitated the development of advanced detection techniques that might provide increased sensitivity, better selectivity, and more information about the identity, the structure or the elemental composition of the analytes.

The material presented on the next chapters will cover the principles of various detection techniques nowadays used in IC. Although IC includes a variety of separation modes such as ion-exchange, ion-exclusion, ion-pairing, or ion-chelation, the discussion will mainly be restricted to ion-exchange chromatography, which seems to be the currently most widely applied separation mode in IC.


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