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Introduction
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Stationary phases
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Physical & Chemical properties
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Retention and Selectivity
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Chemical and thermal stability
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Reproducibility and repeatability
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Hybrid stationary phases
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Mobile phase composition
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How to select the right column
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Column ranking & selection guidance
- > Introduction
- > Selecting a column
- > Columns & manufacturers
- > Experimental
- > Test 1. Neutral compounds
- > Test 2. Acidic compounds
- > Test 3. Basic compounds, high pKa
- > Test 4. Basic compounds, pH 7
- > Test 5. Basic compounds, pH 3
- > Test 6. Metal impurities
- > Test 7. Shape selectivity
- > Test 8. Tanaka hydrogen bonding
- > Conclusions and references
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Column selection for pharma and compendial analysis
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Advanced: RPLC Retention Models
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